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ViroCell, UCL Enter CAR T-cell Therapy Manufacturing Pact

ViroCell will provide the manufacturing of high-specificity lentiviral vectors for UCL’s Phase I clinical trial in pediatric ALL.

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By: Kristin Brooks

Managing Editor, Contract Pharma

ViroCell Biologics, a specialist viral vector CDMO for cell and gene therapy clinical trials, entered into a partnership with University College London (UCL) to advance a chimeric antigen receptor (CAR) T-cell therapy for relapsed pediatric acute lymphoblastic leukemia (ALL). Genetically modified CAR T-cells targeting CD19 have shown impressive outcomes in relapsed/refractory ALL. However, 50% of responding patients will relapse either due to evolution of CD19 negative disease or early loss o...

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